Saturday, April 27, 2013

Google's Neal Mohan On The Keys To Bringing Brand Advertisers Online

neal mohanNeal Mohan, Google's vice president of display advertising, said that his "top priority" for 2013 is bring brand advertising online in a big way. I interviewed Mohan as part of the preparation for our panel at Disrupt NY next week, where we'll discuss the ad landscape with Gokul Rajaram, Facebook's product director for ads, and Kevin Weil, Twitter's senior director of revenue products. During our Q&A covered Google's relationship with brand marketers, mobile and multi-screen advertising, and today's announcement that Google's Active View metric, which measures whether an ad was actually viewed (not just served) has been accredited by the Media Rating Council.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/JKmieG8zaq4/

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Military grooms new officers for war in cyberspace

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Source: http://www.labspaces.net/127943/Military_grooms_new_officers_for_war_in_cyberspace

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Oil production rises for Exxon, Conoco in first-quarter

By Anna Driver

HOUSTON (Reuters) - Quarterly results from Exxon Mobil Corp and ConocoPhillips on Thursday showed that while overall growth remained elusive, output rose in key basins in the United States where the oil and gas companies are spending heavily to grow crude production.

North American shale basins and the Gulf of Mexico are seen as more secure places for energy companies to invest because they typically offer a steady source of growth. Conoco said in December that more than half of its nearly $16 billion budget for 2013 will be spent in North America.

Exxon's U.S. oil and natural gas liquids production rose 2 percent in the first quarter, compared with an overall output decline of 3.5 percent.

"Lower production at Exxon is an ongoing trend, they need so many projects to come online to offset field decline," said Brian Youngberg, energy company analyst at Edward Jones. "But Conoco's shift toward the U.S. continues to proceed well."

Conoco said oil and gas production rose a combined 42 percent in the Bakken Shale in North Dakota and Texas' Permian Basin and Eagle Ford Shale. Conoco's total output from continuing operations edged 1 percent lower.

Fourth-largest U.S. oil company Occidental Petroleum Corp said its daily domestic oil and gas production rose to a record 478,000 barrels of oil equivalent (boe), most of which was oil or natural gas liquids.

"WEAK" BEAT

Exxon's quarterly profit edged up, helped by higher earnings in its chemicals business but oil and gas production fell.

Earnings per share for the world's largest publicly traded oil company topped Wall Street expectations but the gains largely came after a big stock buyback reduced the number of outstanding shares.

Analysts at Credit Suisse characterized it as a "weak" beat in a note to clients.

Exxon said it will lower its quarterly share buyback to $4 billion in the second quarter, below the $5 billion in the first quarter.

First-quarter profit for the world's largest publicly traded oil company was $2.12 per share. Analysts, on average, expected the Irving, Texas, company to report a profit of $2.05 per share.

Conoco's first-quarter results met Wall Street expectations and Occidental beat the Street, helped by higher profits in its midstream and marketing business and lower costs, analysts said.

Conoco had a first-quarter profit of $2.1 billion, or $1.73 per share, down from $2.9 billion, or $2.27 per share, a year earlier.

Occidental reported a first-quarter net profit of $1.36 billion, or $1.68 per share, compared with $1.56 billion, or $1.92 per share, a year earlier.

Excluding items, the Los Angeles company earned $1.69 per share, topping analysts' average estimate of $1.54 per share, according to Thomson Reuters I/B/E/S.

Shares of Exxon fell nearly 1 percent to $88.62. Conoco shares edged down 6 cents to $58.19 and Occidental was up 8 cents to $84.41.

(Reporting By Anna Driver; Editing by Nick Zieminski)

Source: http://news.yahoo.com/oil-production-rises-exxon-conoco-first-quarter-152527150--finance.html

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Friday, April 26, 2013

D is for Dentist: get happy series: start it up.

Our fitness challenge wrapped up this week! I began this challenge beginning of this semester with my vegetarian transition, maybe a little too ambitiously. With a busy dental school schedule and marathon training, I spent a lot of time stressing out about what I should be doing. I had actually gained weight!

I chatted with Sharon right after my weigh-in. She set me off to deep thought about the way I think about health and fitness. An interview with her, our inaugural SHAPE challenge winner!!!, will be coming up soon- meanwhile, you can read her interview about her HPSP (military scholarship for dental school) here.

Being healthy isn?t just about weighing a certain number or looking a certain way. This is why I?m excited to start this ?Get happy series?. (I took this picture on my run crossing the bridge to New Jersey!- Philadelphia looked so beautiful with the sun setting in the background.)

gethappy

I?ll be write about health, physical fitness, nutrition, dentist ergonomics and emotional health***: many things I should pay more attention to. To start off, here?s my baseline right now with a busy school schedule.

  • I sit on average 8 hours a day at school + 3-5 hours studying/working/writing.

  • I walk about 3000 steps on average on days I don?t run.

  • I snack throughout the day into the night out of fatigue-boredom-stress.

I want to focus more on the mental/emotional health on this dental school journey. Once school lightens up a bit I?m going to organize and structure this blog a bit, so look forward to new changes.

I?m heading to DC tomorrow morning bright and early to tackle 13.1 miles. Sleep tight, everyone! Please send me some badass running vibes!!!

Source: http://www.disfordentist.com/2013/04/get-happy-series-start-it-up.html

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Battery of tests on cancer cells shows them as 'squishy,' yet tactically strong

Apr. 26, 2013 ? A team of student researchers and their professors from 20 laboratories around the country have gotten a new view of cancer cells. The work could shed light on the transforming physical properties of these cells as they metastasize, said Jack R. Staunton, a Ph.D. candidate at Arizona State University in the lab of Prof. Robert Ros, and the lead author of a paper reporting on the topic.

Metastasis is a critical step in the progression of cancer. It is when the cancer spreads from one organ or part to another. While much is known about metastasis, it remains an incomplete understanding of the physical biology of the transition.

To get a better understanding of metastasis, more than 95 graduate students, post docs and professors in a variety of laboratories across the U.S. subjected two cell lines to a battery of high-tech tests and measurements. Their results were published April 26, 2013 in Scientific Reports.

The researchers performed coordinated molecular and biophysical studies of non-malignant and metastatic breast cell lines to learn more about what happens to a cell when it transitions to a metastatic state.

Each laboratory is part of the National Cancer Institute's Physical Sciences Oncology Center (PSOC), a network of 12 centers devoted to understanding the physical sciences of cancer. ASU's center, the Center for the Convergence of Physical Science and Cancer Biology, is led by Prof. Paul Davies.

Each PS-OC was supplied with identical cell lines and common reagents, and considerable effort was made to ensure that all the conditions were standardized and documented at regular intervals. Staunton said the ASU group made three contributions to the study.

Other ASU researchers involved in the project and co-authors on the paper are: Alexander Fuhrmann, Vivek Nandakumar, Laimonas Kelbauskas, Patti Senechal, Courtney Hemphill, Roger H. Johnson and Deirdre Meldrum.

"We compared the stiffness of normal breast cells and highly metastatic breast cancer cells, and found the cancer cells to be significantly more 'squishy' or deformable," Staunton said. "This makes sense because in order for a cell to metastasize, it has to squeeze through tight passages in the lymphatics and microvasculature, so being squishy helps cancer cells spread through the body."

"We also looked at the morphology of their nuclei," he added. "The cancer cell nuclei were found to have a characteristic 'crushed beach-ball' shape that might correspond to the abnormal chromosomal rearrangements associated with cancer."

"Finally, we took individual cells, put each one in an airtight chamber, and measured how much oxygen they consumed," Staunton said. "This tells us about their metabolism. We found the cancer cells use less oxygen, relying more on glycolysis, kind of like what bacteria and yeast do."

Taken together, researchers at the 12 PSOC's used some 20 distinct techniques, including atomic force microscopy, ballistic intracellular nano-rheology, cell surface receptor expression levels, differential interference contrast microscopy, micro-patterning and extracellular matrix secretion, and traction force microscopy.

The work has enabled a comprehensive cataloging and comparison of the physical characteristics of non-malignant and metastatic cells, and the molecular signatures associated with those characteristics. This made it possible to identify unique relationships between observations, Staunton said.

"We were surprised that even though the cancer cells are softer, they are able to exert more contractile forces on the fibers surrounding them -- which was determined at the Cornell University PSOC by a method called traction force microscopy. This pair of characteristics is somewhat contradictory from a purely physical perspective, but it makes sense for a cancer cell, since both traits improve their chances of metastasizing. Understanding why is still an active area of research," explained Staunton, who is working towards his doctorate in physics.

"Another interesting finding was that a protein called CD44, which doubles as a cancer stem cell marker and as a molecule that helps the cell stick to certain fibers in the extracellular matrix, is equally abundant in the normal and cancer cells. But in the cancer cells the proteins don't make it to the cell surface," he added.

"For some reason they stay inside the cytoplasm, so the cancer cells are not as sticky," added Staunton whose hometown is Buffalo, N.Y. "This is another trait that contributes to their ability to spread through the body."

The PSOC network went to great lengths to have all of the studies performed under comparable conditions. While the cell lines studied are well understood, part of the effort for the network was to prove they could consistently coordinate the research.

Staunton, who has been involved in ASU's center since its inception, says the experience has helped his growth as a researcher.

"It is the perfect habitat for budding scientists and for transdisciplinary collaborations," he said.

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Story Source:

The above story is reprinted from materials provided by Arizona State University, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. David B. Agus, Jenolyn F. Alexander, Wadih Arap, Shashanka Ashili, Joseph E. Aslan, Robert H. Austin, Vadim Backman, Kelly J. Bethel, Richard Bonneau, Wei-Chiang Chen, Chira Chen-Tanyolac, Nathan C. Choi, Steven A. Curley, Matthew Dallas, Dhwanil Damania, Paul C. W. Davies, Paolo Decuzzi, Laura Dickinson, Luis Estevez-Salmeron, Veronica Estrella, Mauro Ferrari, Claudia Fischbach, Jasmine Foo, Stephanie I. Fraley, Christian Frantz, Alexander Fuhrmann, Philippe Gascard, Robert A. Gatenby, Yue Geng, Sharon Gerecht, Robert J. Gillies, Biana Godin, William M. Grady, Alex Greenfield, Courtney Hemphill, Barbara L. Hempstead, Abigail Hielscher, W. Daniel Hillis, Eric C. Holland, Arig Ibrahim-Hashim, Tyler Jacks, Roger H. Johnson, Ahyoung Joo, Jonathan E. Katz, Laimonas Kelbauskas, Carl Kesselman, Michael R. King, Konstantinos Konstantopoulos, Casey M. Kraning-Rush, Peter Kuhn, Kevin Kung, Brian Kwee, Johnathon N. Lakins, Guillaume Lambert, David Liao, Jonathan D. Licht, Jan T. Liphardt, Liyu Liu, Mark C. Lloyd, Anna Lyubimova, Parag Mallick, John Marko, Owen J. T. McCarty, Deirdre R. Meldrum, Franziska Michor, Shannon M. Mumenthaler, Vivek Nandakumar, Thomas V. O?Halloran, Steve Oh, Renata Pasqualini, Matthew J. Paszek, Kevin G. Philips, Christopher S. Poultney, Kuldeepsinh Rana, Cynthia A. Reinhart-King, Robert Ros, Gregg L. Semenza, Patti Senechal, Michael L. Shuler, Srimeenakshi Srinivasan, Jack R. Staunton, Yolanda Stypula, Hariharan Subramanian, Thea D. Tlsty, Garth W. Tormoen, Yiider Tseng, Alexander van Oudenaarden, Scott S. Verbridge, Jenny C. Wan, Valerie M. Weaver, Jonathan Widom, Christine Will, Denis Wirtz, Jonathan Wojtkowiak, Pei-Hsun Wu. A physical sciences network characterization of non-tumorigenic and metastatic cells. Scientific Reports, 2013; 3 DOI: 10.1038/srep01449

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/bVQjS3PQ97M/130426135034.htm

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Short-seller Chanos still bearish on PC-makers Dell, HP: CNBC

NEW YORK (Reuters) - Hedge fund manager James Chanos told CNBC on Wednesday that he was still betting against the shares of computer-makers Dell and Hewlett-Packard.

Chanos, noted for predicting the downfall of Enron and more recently a vocal bear on the Chinese economy, told CNBC that the "PC (personal computer) business is falling apart" and the industry faces structural problems.

"The real structural issue is these companies are behind the eight-ball," Chanos said. "The secular story has not gone away."

Chanos, who is president and founder of short-selling firm Kynikos Associates, has criticized Hewlett Packard for failing to keep up with competitors in the mobile and cloud computing space.

The hedge fund manager said his roughly $6 billion firm had gotten out of its Dell trade last year, then began to short the stock again in 2013. If a hedge fund manager is short a stock, he believes its price will fall.

"I shorted into the deal," Chanos said, referring to a $24.4 billion deal to take the company private for $13.65 a share.

"I'm puzzled as a financial analyst and a business analyst why this is an attractive deal," he added, noting that Dell's "cash flow is plummeting."

He said his New York-based firm has a small long position in iPad maker Apple Inc, and added he had never shorted that technology company.

Chanos also told CNBC that nutritional supplement company Herbalife is "not a viable business long-term."

Herbalife has been at the center of a war-of-words between two well-known hedge fund managers William Ackman and Carl Icahn, who are short and long the stock respectively.

Chanos, who had a short position in Herbalife in 2012 and closed out position in the fourth quarter, said the "multi-level marketing model is flawed."

(Reporting by Katya Wachtel; Editing by David Gregorio and Bob Burgdorfer)

Source: http://news.yahoo.com/short-seller-chanos-still-bearish-pc-makers-dell-170158351--sector.html

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Scientists image nanoparticles in action

Apr. 25, 2013 ? The macroscopic effects of certain nanoparticles on human health have long been clear to the naked eye. What scientists have lacked is the ability to see the detailed movements of individual particles that give rise to those effects.

In a recently published study, scientists at the Virginia Tech Carilion Research Institute invented a technique for imaging nanoparticle dynamics with atomic resolution as these dynamics occur in a liquid environment. The results will allow, for the first time, the imaging of nanoscale processes, such as the engulfment of nanoparticles into cells.

"We were stunned to see the large-ranged mobility in such small objects," said Deborah Kelly, an assistant professor at the Virginia Tech Carilion Research Institute. "We now have a system to watch the behaviors of therapeutic nanoparticles at atomic resolution."

Nanoparticles are made of many materials and come in different shapes and sizes. In the new study, Kelly and her colleagues chose to make rod-shaped gold nanoparticles the stars of their new molecular movies. These nanoparticles, roughly the size of a virus, are used to treat various forms of cancer. Once injected, they accumulate in solid tumors. Infrared radiation is then used to heat them and destroy nearby cancerous cells.

To take an up-close look at the gold nanoparticles in action, the researchers made a vacuum-tight microfluidic chamber by pressing two silicon-nitride semiconductor chips together with a 150-nanometer spacer in between. The microchips contained transparent windows so the beam from a transmission electron microscope could pass through to create an atomic-scale image.

Using the new technique, the scientists created two types of visualizations. The first included pictures of individual nanoparticles' atomic structures at 100,000-times magnification -- the highest resolution images ever taken of nanoparticles in a liquid environment.

The second visualization was a movie captured at 23,000-times magnification that revealed the movements of a group of nanoparticles reacting to an electron beam, which mimics the effects of the infrared radiation used in cancer therapies.

In the movie, the gold nanoparticles can be seen surfing nanoscale tidal waves.

"The nanoparticles behaved like grains of sand being concentrated on a beach by crashing waves," said Kelly. "We think this behavior may be related to why the nanoparticles become concentrated in tumors. Our next experiment will be to insert a cancer cell to study the nanoparticles' therapeutic effects on tumors."

The team is also testing the resolution of the microfluidic system with other reagents and materials, bringing researchers one step closer to viewing live biological mechanisms in action at the highest levels of resolution possible.

The study appeared in the April 14 print edition of Chemical Communications in the article "Visualizing Nanoparticle Mobility in Liquid at Atomic Resolution," by Madeline Dukes, an applications scientist at Protochips Inc. in Raleigh, N.C.; Benjamin Jacobs, an applications scientist at Protochips; David Morgan, assistant manager of the Cryo-Transmission Electron Microscopy Facility at Indiana University Bloomington; Harshad Hegde, a computer scientist at the Virginia Tech Carilion Research Institute; and Kelly, who is also an assistant professor of biological sciences in the College of Science at Virginia Tech.

Video: http://research.vtc.vt.edu/videos/2013/apr/11/nanoparticles-action/

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Story Source:

The above story is reprinted from materials provided by Virginia Tech. The original article was written by Ken Kingery.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Madeline J. Dukes, Benjamin W. Jacobs, David G. Morgan, Harshad Hegde, Deborah F. Kelly. Visualizing nanoparticle mobility in liquid at atomic resolution. Chemical Communications, 2013; 49 (29): 3007 DOI: 10.1039/C3CC41136B

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_science/~3/SJCcdpS4XPc/130425142436.htm

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Thursday, April 25, 2013

US-MUSIC Summary

Mamma Mia! Bookie offers odds on ABBA reunion

LONDON (Reuters) - A British bookmaker is taking bets on an ABBA comeback after singer Agnetha Faltskog hinted at a possible reunion for Sweden's most successful band. Faltskog, who has come out of retirement to release a solo album called "A", was asked by German's Die Zeit Magazine if she would be open to an ABBA reunion and she responded positively.

Psy knocked from top of Korean charts by 63-year-old singer

SEOUL (Reuters) - South Korean rapper Psy, whose latest video "Gentleman" tracked global megahit "Gangnam Style" by going viral on the Internet, has been knocked from the top of the music charts in his native country by a 63-year-old easy listening pop singer. "Gangnam Style", which holds the YouTube record for most views with more than 1.5 billion, catapulted the sunglassed Korean with the garish jackets to world stardom and made him one of the best-known faces to grace the growing K-pop music scene.

Documentary about deceased British singer Amy Winehouse in the works

(Reuters) - A documentary is in the works about the late British soul singer Amy Winehouse and it features previously unseen material, the film's distributor said on Wednesday. The film, which will include archival footage never seen by the public, will be directed by Briton Asif Kapadia, whose 2010 film "Senna," about Brazilian auto racer Ayrton Senna, won a BAFTA for best documentary.

Kurdish singer sparks identity debate on Arab talent show

ARBIL, Iraq (Reuters) - A singer from Iraq's Kurdistan region has made it through to the semi-final of an Arab talent contest, igniting heated debates over Iraqi identity and politicizing the popular TV show. A panel of judges praised 24-year-old Parwaz Hussein and she was voted through to the next round of "Arab Idol", in which aspiring popstars from Morocco to Bahrain compete for a recording contract.

Swedish police find drugs on Justin Bieber bus, no suspects

STOCKHOLM (Reuters) - Swedish police said on Thursday they found drugs on teen idol Justin Bieber's tour bus in Stockholm, but had no suspects and were unlikely to pursue the case further. A police officer on crowd duty smelled marijuana on an empty tour bus outside the hotel where Bieber was staying just before his concert in the capital on Wednesday night, police spokesman Kjell Lindgren said.

Michael Jackson wrongful death trial set to get underway Monday

LOS ANGELES (Reuters) - The civil trial over the death of Michael Jackson is set to get formally underway next week after jury selection was completed on Tuesday in the $40 billion case that pits the pop star's mother against concert promoters AEG Live. Six alternate jurors were chosen on Tuesday following the selection a day earlier of a jury of six men and six women for what is expected to be an emotional three-month trial.

Fall Out Boy outsells Kid Cudi for top spot on Billboard chart

LOS ANGELES (Reuters) - U.S. rock band Fall Out Boy topped the Billboard 200 weekly best-selling album chart for the second time in their five-album career, besting rapper Kid Cudi. "Save Rock and Roll" sold 154,000 copies in its debut week, according figures on Wednesday from Nielsen SoundScan, outpacing Kid Cudi's "Indicud," which sold 136,000 copies in its first week.

Singer Lauryn Hill gets reprieve on tax evasion sentencing

NEWARK (Reuters) - Grammy Award-winning singer Lauryn Hill was given a two-week reprieve on her sentencing for federal tax evasion on Monday as a federal judge admonished her defense counsel for failing to come up with most of the tax money promised prior to her scheduled hearing. Hill, a solo artist and a member of the Fugees rap trio, pleaded guilty in June 2012 to failure to file federal tax returns from 2005-2007, when she earned $1.8 million. She faces up to a year in prison for each charge.

Backstreet Boys get Hollywood star ahead of world tour

LOS ANGELES (Reuters) - Boy band the Backstreet Boys - now all grown men - on Monday marked their 20th anniversary and their upcoming world tour by getting a star on the Hollywood Walk of Fame. "Backstreet is Back ... and we aren't going anywhere," Nick Carter, 33, told fans as all five members of the 1990s band gathered to unveil their star - located right next to another popular boy band, Boyz II Men.

Folk musician Richie Havens dead at 72

LOS ANGELES (Reuters) - U.S. folk musician Richie Havens, who opened the historic 1969 Woodstock musical festival and energized the crowd with his version of "Motherless Child/Freedom," died of a heart attack on Monday at the age of 72, his talent agency said. Havens, who emerged from the New York folk scene in the 1960s and went on to sing for the Dalai Lama and President Bill Clinton, died at his home in Jersey City, New Jersey, Roots Agency President Tim Drake told Reuters.

Source: http://news.yahoo.com/us-music-summary-081908906.html

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Take These Slick Journals for a Dip

Makr's sketchbooks aren't the type of girl that goes to the pool just to catch some rays in a fancy bikini. They're water-resistant, so a little splash won't hurt them. And they look great too. More »
    


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/Lh48EQQdQxk/take-these-slick-journals-for-a-dip

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4 charged after Va. freshmen swept into river

PETERSBURG, Va. (AP) ? Police arrested three men and sought a fourth Tuesday after two Virginia State University freshmen were swept away while trying to cross a swift, rain-swollen river as part of an initiation rite.

The body of one freshman, identified as Marvell Edmonson, 19, of Portsmouth, was recovered Monday. The search continued Tuesday for the second, Jauwan M. Holmes, 19, of Newport News.

The four suspects are connected to an organization known as "Men of Honor" that conducted an initiation Saturday that required seven male VSU students to walk through the rushing rapids of the Appomattox River, police said. While some were pulled to safety, two were swept away.

Chesterfield County police identified the three in custody as James A. Mackey Sr., 35, of suburban Richmond; Eriq K. Benson, 19, of Quinton; and Cory D. Baytop, 26, of Newport News. Each has been charged with five counts of hazing. Police were seeking Charles E. Zollicoffer II, 29. An address was not provided.

Benson and Baytop are VSU students. Benson's attorney did not immediately return a telephone message. It was not clear if the other suspects had attorneys.

Police Lt. Randy Horowitz described Men of Honor as a social club or "group whose mission is to build the character of young men." He said he was not familiar with the organization beyond that, and said it was not sanctioned by VSU.

University spokesman Thomas Reed said Men of Honor was not affiliated with VSU and he could provide no additional information on it. Students are provided with information about sanctioned groups on the campus, he said.

Reed declined to discuss the arrests or the two students accused, citing the investigation. He acknowledged that the school has had problems with hazing in the past and has taken steps to eliminate it.

In April, the president of the student government association was charged with hazing related to an incident off campus in neighboring Petersburg in August 2012.

In 2009, six VSU students and two nonstudents were accused of hazing after another student sought medical treatment for severe bruising. In a plea agreement, the defendants agreed to prepare and present information sessions for students at VSU in exchange for the eventual dismissal of the charges.

The historically black university has about 5,300 students in Ettrick, about 25 miles south of Richmond.

Source: http://news.yahoo.com/4-charged-va-freshmen-swept-river-222542738.html

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Artists transform sand on a Florida beach

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